Kohji Takei Selected Research

N'- (3,4- dihydroxybenzylidene)- 3- hydroxy- 2- naphthahydrazide

11/2016	Dynamin2 GTPase contributes to invadopodia formation in invasive bladder cancer cells.
1/2014	N'-[4-(dipropylamino)benzylidene]-2-hydroxybenzohydrazide is a dynamin GTPase inhibitor that suppresses cancer cell migration and invasion by inhibiting actin polymerization.
12/2009	Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments.

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Kohji Takei Research Topics

Disease

9	Neoplasms (Cancer) 11/2016 - 12/2009
4	Urinary Bladder Neoplasms (Bladder Cancer) 11/2016 - 07/2012
3	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2022 - 01/2012
3	Glioma (Gliomas) 01/2020 - 03/2016
3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2016 - 01/2014
2	Carcinogenesis 01/2019 - 04/2008
2	Lung Neoplasms (Lung Cancer) 09/2016 - 12/2009
2	Fibrosis (Cirrhosis) 01/2016 - 01/2014
2	Body Weight (Weight, Body) 01/2016 - 01/2014
2	Inherited Peripheral Neuropathy 01/2016 - 06/2009
2	Hyperglycemia 01/2016 - 01/2014
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016 - 10/2005
2	Neuroblastoma 09/2015 - 03/2013
2	Inflammation (Inflammations) 01/2014 - 01/2014
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Congenital Structural Myopathies (Centronuclear Myopathy) 01/2021
1	Infections 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2016
1	Neoplasm Metastasis (Metastasis) 09/2016
1	Drug-Related Side Effects and Adverse Reactions 03/2016
1	Brain Neoplasms (Brain Tumor) 03/2016
1	Glioblastoma (Glioblastoma Multiforme) 03/2016
1	Obesity 01/2016
1	Type 2 Diabetes Mellitus (MODY) 01/2014
1	Albuminuria 01/2014
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2012
1	Genetic Translocation (Chromosomal Translocation) 01/2012
1	Anemia 01/2012
1	Gingival Overgrowth 10/2007
1	Seizures (Absence Seizure) 06/2007
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 10/2005
1	Vascular Diseases (Vascular Disease) 11/2004
1	Atherosclerosis 11/2004
1	Hemolytic Anemia 10/2003
1	Reticulocytosis 10/2003

Drug/Important Bio-Agent (IBA)

7	Dynamins (Dynamin)IBA 01/2022 - 12/2009
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2008
6	Dynamin IIIBA 01/2022 - 11/2004
5	CortactinIBA 01/2020 - 03/2013
3	GTP Phosphohydrolases (GTPases)IBA 11/2016 - 12/2009
3	N'- (3,4- dihydroxybenzylidene)- 3- hydroxy- 2- naphthahydrazideIBA 11/2016 - 12/2009
3	Hemoglobins (Hemoglobin)IBA 01/2016 - 10/2003
3	Blood Glucose (Blood Sugar)IBA 01/2016 - 10/2005
3	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 01/2014
2	CyclinsIBA 01/2020 - 01/2019
2	Protein Isoforms (Isoforms)IBA 11/2016 - 09/2016
2	Actins (F Actin)IBA 09/2016 - 12/2009
2	Sodium-Glucose Transport ProteinsIBA 01/2016 - 01/2014
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2016 - 01/2014
2	AlbuminsIBA 01/2016 - 01/2014
2	dapagliflozinIBA 01/2016 - 01/2014
2	Streptozocin (Streptozotocin)FDA Link 01/2014 - 10/2005
2	Antineoplastic Agents (Antineoplastics)IBA 01/2013 - 08/2012
1	LipidsIBA 01/2022
1	Adenosine Triphosphatases (ATPase)IBA 01/2019
1	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 01/2019
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 03/2016
1	TOR Serine-Threonine KinasesIBA 03/2016
1	Pharmaceutical PreparationsIBA 03/2016
1	Fluvoxamine (Luvox)FDA LinkGeneric 03/2016
1	Insulin (Novolin)FDA Link 01/2016
1	Coxsackie and Adenovirus Receptor-Like Membrane ProteinIBA 01/2016
1	Protein Kinase CIBA 09/2015
1	CreatinineIBA 01/2014
1	MetallothioneinIBA 01/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014
1	Small Interfering RNA (siRNA)IBA 01/2014
1	Dynamin IIBA 03/2013
1	Biological ProductsIBA 01/2013
1	Cisplatin (Platino)FDA LinkGeneric 01/2013
1	Surface Antigens (Surface Antigen)IBA 01/2013
1	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2012
1	Growth InhibitorsIBA 08/2012
1	tumor-associated transplantation antigen (TSTA)IBA 07/2012
1	Green Fluorescent ProteinsIBA 07/2012
1	LuciferasesIBA 07/2012
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2012
1	IronIBA 01/2012
1	ClathrinIBA 01/2012
1	Vesicular Transport Adaptor ProteinsIBA 01/2012
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 10/2007
1	Immunosuppressive Agents (Immunosuppressants)IBA 10/2007
1	Kainic Acid (Kainate)IBA 06/2007
1	amphiphysinIBA 06/2007
1	CalpainIBA 06/2007
1	oxidized low density lipoproteinIBA 11/2004
1	phenylhydrazine (phenylhydrazine hydrochloride)IBA 10/2003
1	ProtoporphyrinsIBA 10/2003
1	Heme (Haem)IBA 10/2003

Therapy/Procedure

1	Intravesical Administration 08/2012
1	Therapeutics 10/2005
1	Transplantation 10/2005